Description

4-Isopropylidene-2,2,3,3-Tetramethylcyclobutanone is a specialized, high-purity cyclobutanone derivative characterized by its unique sterically hindered structure. This compound serves as a critical advanced intermediate in fine chemical synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly those requiring rigid, sterically defined frameworks.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its unique structure can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and organometallic chemistry.
• Polymer & Material Science: Employed in the synthesis of monomers for high-performance polymers with tailored thermal and mechanical properties.
• Fragrance & Flavor Chemistry: Acts as an intermediate for creating complex, musky, or woody odorant molecules due to its polyalkylated cyclobutanone core.
• Organic Synthesis Research: A valuable reagent for studying ring-strain reactions and developing new methodologies in academic and industrial laboratories.

Basic Information

Product Name	4-Isopropylidene-2,2,3,3-Tetramethylcyclobutanone
CAS No.	4868-12-6
Molecular Formula	C11H18O
Molecular Weight	166.26 g/mol
Synonyms	2,2,3,3-Tetramethyl-4-isopropylidenecyclobutanone; 4-(Propan-2-ylidene)-2,2,3,3-tetramethylcyclobutan-1-one; Tetramethylisopropylidenecyclobutanone; 4-Isopropylidene-2,2,3,3-tetramethyl-1-cyclobutanone; 1-Cyclobutanone, 4-isopropylidene-2,2,3,3-tetramethyl-
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including GC, HPLC, and NMR, to verify identity and purity against stringent internal specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.