Description

3α-(Trimethylsiloxy)-5β-Androstan-17-One is a high-purity steroid derivative and a key synthetic intermediate in organic chemistry. This compound is valued for its role in the synthesis of more complex steroid-based molecules, offering a protected functional group for precise chemical transformations. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), hormone analogs, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of steroidal drugs and hormone analogs.
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and creating novel steroid derivatives.
• Fine Chemical Synthesis: Serves as a precursor in the production of specialized fine chemicals and reference standards.
• Process Chemistry: Employed in scale-up and process optimization for the manufacture of advanced steroid compounds.

Basic Information

Product Name	3α-(Trimethylsiloxy)-5β-Androstan-17-One
CAS No.	4867-14-5
Molecular Formula	C22H38O2Si
Molecular Weight	362.62 g/mol
Synonyms	3α-(Trimethylsilyloxy)-5β-androstan-17-one; 5β-Androstan-17-one, 3α-(trimethylsilyloxy)-; 3α-Hydroxy-5β-androstan-17-one 3-trimethylsilyl ether; 3-TMS-androsterone; Androsterone 3-trimethylsilyl ether; 3α-Trimethylsiloxyetioallocholan-17-one; 17-Oxo-5β-androstan-3α-yloxytrimethylsilane
EINECS	Contact for details

Quality Control

Our 3α-(Trimethylsiloxy)-5β-Androstan-17-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.