Description

2-Chlorocyclooctanone is a versatile halogenated cyclic ketone building block of significant interest in advanced organic synthesis. Its value lies in the strategic combination of a reactive carbonyl group and a chlorine substituent on an eight-membered ring, enabling complex ring transformations and functionalizations. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of novel molecular architectures and as a key intermediate in multi-step synthetic routes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex bioactive molecules, including potential drug candidates with bridged or medium-sized ring systems.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the chloroketone moiety can be leveraged for further derivatization.
• Organic Synthesis Building Block: Employed in ring-expansion, ring-contraction, and annulation reactions to construct challenging carbocyclic and heterocyclic frameworks.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or mechanical properties.
• Catalysis & Ligand Synthesis: Utilized for the preparation of novel chiral ligands or organocatalysts, particularly those based on medium-ring scaffolds.
• Fragrance & Flavor Chemistry: Investigated as an intermediate for the synthesis of macrocyclic musk compounds and other specialty aroma chemicals.

Basic Information

Product Name	2-Chlorocyclooctanone
CAS No.	4828-34-6
Molecular Formula	C8H13ClO
Molecular Weight	160.64 g/mol
Synonyms	2-Chlorocyclooctan-1-one; Cyclooctanone, 2-chloro-; 2-Chloro-1-cyclooctanone; 2-Chlorocyclooctan-1-one; α-Chlorocyclooctanone
EINECS	Contact for details

Quality Control

Our 2-Chlorocyclooctanone is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assessment and structural confirmation. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.