Description

(2S,5S)-Tetrahydro-4-Oxo-5,N,N,n-Tetramethyl-2-Furanmethanaminium is a high-purity, chiral ammonium salt derivative of a tetrahydrofuranone, identified by CAS number 4780-69-2. This compound is valued for its role as a key chiral intermediate and building block in sophisticated organic synthesis, particularly in the pharmaceutical sector. It is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), asymmetric catalysis, and the development of novel fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a chiral auxiliary or catalyst component in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, agrochemicals, and advanced materials.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of chiral substances.

Basic Information

Product Name	(2S,5S)-Tetrahydro-4-Oxo-5,N,N,n-Tetramethyl-2-Furanmethanaminium
CAS No.	4780-69-2
Molecular Formula	C10H20NO2+ (typically as a salt, e.g., chloride)
Molecular Weight	186.27 g/mol (for the cation)
Synonyms	(2S,5S)-5-(Dimethylamino)tetrahydro-4-oxo-2-furanmethyltrimethylammonium; 2-(Trimethylammonium)methyl-5-(dimethylamino)-2,5-dihydro-2-furanone; (2S-cis)-Tetrahydro-4-oxo-5-(dimethylamino)-2-furanmethyltrimethylammonium; L-Carnitine intermediate derivative; (2S,5S)-5-(N,N-Dimethylamino)-2-(trimethylammoniomethyl)tetrahydrofuran-4-one
EINECS	Contact for details

Quality Control

Our (2S,5S)-Tetrahydro-4-Oxo-5,N,N,n-Tetramethyl-2-Furanmethanaminium is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and chiral integrity, meeting the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored in a cool, dry place. For long-term stability, store at 2-8°C under an inert atmosphere. Keep the container tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.