Description

1-Amino-3-(3-Fluorophenoxy)Propan-2-Ol is a versatile fluorinated amino alcohol building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of β-blockers, adrenergic agents, and other bioactive molecules containing a phenoxypropanolamine core structure.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a chiral building block for creating sophisticated ligands used in asymmetric catalysis and metal complexation.
• Polymer Modification: Employed to introduce amino and hydroxyl functional groups into polymer chains, modifying properties like adhesion, solubility, and reactivity.
• Research & Development: A valuable reagent for medicinal chemistry programs exploring structure-activity relationships (SAR) in drug discovery.
• Fine Chemical Production: Integral to multi-step synthetic routes for producing complex fluorinated organic compounds.

Basic Information

Item	Details
Product Name	1-Amino-3-(3-Fluorophenoxy)Propan-2-Ol
CAS No.	4764-34-5
Molecular Formula	C9H12FNO2
Molecular Weight	185.20 g/mol
Synonyms	3-(3-Fluorophenoxy)-2-hydroxypropylamine; 1-Amino-3-(3-fluorophenoxy)-2-propanol; 3-Fluoro-α-[(1-methylethyl)amino]methyl]benzenemethanol (related isomer); 3-Fluorophenoxypropanolamine; FPPA; 2-Propanol, 1-amino-3-(3-fluorophenoxy)-; (RS)-1-Amino-3-(3-fluorophenoxy)propan-2-ol
EINECS	Contact for details

Quality Control

Our 1-Amino-3-(3-Fluorophenoxy)Propan-2-Ol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.