Description

1-(Hydroxymethyl)-3-[(5-Nitrofurfurylidene)Amino]-2-Imidazolidinethione is a specialized heterocyclic organic compound that serves as a key synthetic intermediate and active pharmaceutical ingredient (API) precursor. Its molecular structure, featuring a nitrofuran moiety and an imidazolidinethione ring, is central to its biological activity and utility in advanced chemical synthesis. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents. We supply this material with a focus on high purity, batch-to-batch consistency, and reliable global logistics to support critical R&D and production processes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antimicrobial and antiparasitic drug candidates, leveraging the bioactive nitrofuran scaffold.
• Agrochemical Research: Used in the development of next-generation fungicides and bactericides for crop protection, targeting specific enzymatic pathways.
• Biochemical Research: Employed as a tool compound in microbiological and enzymatic studies to investigate mechanisms of action and resistance.
• Chemical Synthesis: Acts as a versatile precursor for synthesizing more complex heterocyclic compounds and functionalized molecules in medicinal chemistry.
• Veterinary Medicine Development: Investigated for potential use in formulating treatments for bacterial infections in animals.

Basic Information

Product Name	1-(Hydroxymethyl)-3-[(5-Nitrofurfurylidene)Amino]-2-Imidazolidinethione
CAS No.	4657-19-6
Molecular Formula	C9H10N4O4S
Molecular Weight	270.27 g/mol
Synonyms	Nifursol; 1-Hydroxymethyl-3-[(5-nitrofurfurylidene)amino]-2-imidazolidinethione; 3-[(5-Nitrofurfurylidene)amino]-2-imidazolidinethione-1-methanol; 1-(Hydroxymethyl)-3-[(5-nitrofurfurylidene)amino]-2-thiohydantoin; NFZ; Nitrofurylideneaminoimidazolidinethione; 2-Imidazolidinethione, 1-(hydroxymethyl)-3-[(5-nitrofurfurylidene)amino]-
EINECS	Contact for details

Quality Control

Our 1-(Hydroxymethyl)-3-[(5-Nitrofurfurylidene)Amino]-2-Imidazolidinethione is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for research and synthesis. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.