Description

(4-Hydroxymethyl-2-Methoxy-Phenoxy)-Acetic Acid is a versatile aromatic carboxylic acid derivative with a hydroxymethyl and methoxy functional group on its phenolic ring. This compound is valued as a key synthetic intermediate in the production of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research institutions, fine chemical manufacturers, and companies developing active pharmaceutical ingredients (APIs) or advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or precursor for specialty polymers and liquid crystal materials with specific optical properties.
• Bioconjugation & Linker Chemistry: The hydroxymethyl and carboxylic acid groups make it suitable for creating cleavable linkers in antibody-drug conjugates (ADCs) or other bioconjugation applications.
• Organic Synthesis Research: A valuable reagent for academic and industrial R&D in developing new synthetic methodologies and complex organic structures.
• Dye & Pigment Intermediate: Can be utilized in the synthesis of specialized dyes and organic pigments.

Basic Information

Product Name	(4-Hydroxymethyl-2-Methoxy-Phenoxy)-Acetic Acid
CAS No.	4623-74-9
Molecular Formula	C10H12O5
Molecular Weight	212.20 g/mol
Synonyms	2-Methoxy-4-(hydroxymethyl)phenoxyacetic Acid; Vanillyloxyacetic Acid; (4-Hydroxymethyl-2-methoxyphenoxy)acetic Acid; 4-(Hydroxymethyl)-2-methoxyphenoxyacetic Acid; (2-Methoxy-4-hydroxymethylphenoxy)acetic Acid; Glycolic Acid Vanillyl Ether; Vanillyl Glycolate; Contact for details on additional trade names.
EINECS	225-036-9

Quality Control

Our (4-Hydroxymethyl-2-Methoxy-Phenoxy)-Acetic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.