Description

n-Ethylbenzisoxazolium Tetrafluoroborate is a specialized organic salt primarily used as a key reagent in peptide coupling and other organic synthesis reactions. Its value lies in its role as an efficient coupling agent, facilitating the formation of amide bonds under mild conditions, which is critical for producing high-purity compounds. This product is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and advanced materials sectors that require reliable and high-performance synthetic intermediates.

Application

• As a peptide coupling agent in solid-phase and solution-phase synthesis of pharmaceuticals and bioactive peptides.
• Intermediate in the synthesis of complex organic molecules and active pharmaceutical ingredients (APIs).
• Reagent for amide bond formation in medicinal chemistry and drug discovery research.
• Used in the preparation of specialty chemicals and fine chemicals requiring high selectivity.
• Component in bioconjugation techniques for labeling proteins and other biomolecules.
• Catalyst or activator in specific polymerization and materials science applications.

Basic Information

Product Name	n-Ethylbenzisoxazolium Tetrafluoroborate
CAS No.	4611-62-5
Molecular Formula	C9H10BF4NO
Molecular Weight	235.00 g/mol
Synonyms	1-Ethyl-1H-benzo[d]isoxazol-2-ium tetrafluoroborate; Benzisoxazolium, 1-ethyl-, tetrafluoroborate(1-); Ethylbenzisoxazolium fluoroborate; EBIT; n-Ethylbenzisoxazolium BF4; Coupling Agent EBIT; 1-Ethylbenzisoxazolium Tetrafluoroborate
EINECS	Contact for details

Quality Control

Our n-Ethylbenzisoxazolium Tetrafluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is tested against rigorous in-house specifications, which typically include identification, assay, and impurity profile analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.