Description

2-tert-Butylcyclobutanone is a specialized organic compound featuring a cyclobutanone ring substituted with a bulky tert-butyl group. This unique sterically hindered ketone structure makes it a valuable intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring sterically constrained ketone functionalities.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides where the tert-butylcyclobutanone moiety can impart specific biological activity.
• Fine Chemical Production: Serves as a precursor for manufacturing specialty chemicals, flavors, fragrances, and advanced materials.
• Organic Synthesis Research: Employed in academic and industrial laboratories as a model substrate for studying ring-strain reactions, steric effects in carbonyl chemistry, and developing new catalytic methodologies.
• Ligand and Catalyst Development: Acts as a starting material for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2-tert-Butylcyclobutanone
CAS No.	4579-31-1
Molecular Formula	C8H14O
Molecular Weight	126.20 g/mol
Synonyms	2-(1,1-Dimethylethyl)cyclobutanone; 2-(tert-Butyl)cyclobutanone; 2-tert-Butylcyclobutan-1-one; Cyclobutanone, 2-(1,1-dimethylethyl)-; 2-t-Butylcyclobutanone
EINECS	Contact for details

Quality Control

Our 2-tert-Butylcyclobutanone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.