Description

4-5-Dibromoisothiozole-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its unique dibrominated isothiazole core, which serves as a versatile precursor for constructing complex molecular architectures. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce novel sulfur- and halogen-containing motifs.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Synthesis: Used in the research and production of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a building block for functional polymers, liquid crystals, and organic electronic materials due to its rigid, heteroaromatic structure.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors or receptor modulators.
• Cross-Coupling Reactions: The bromine atoms make it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, or Buchwald-Hartwig couplings to create diverse compound libraries.

Basic Information

Product Name	4-5-Dibromoisothiozole-3-Carboxylic Acid
CAS No.	4576-87-8
Molecular Formula	C4HBr2NO2S
Molecular Weight	282.93 g/mol
Synonyms	4,5-Dibromo-1,2-thiazole-3-carboxylic acid; 4,5-Dibromoisothiazole-3-carboxylic acid; 3-Carboxy-4,5-dibromoisothiazole; 4,5-Dibromo-3-isothiazolecarboxylic acid; 4,5-Dibromo-1,2-thiazole-3-carboxylic acid; Isothiazole-3-carboxylic acid, 4,5-dibromo-; 4,5-Dibromoisothiazole-3-carboxylate
EINECS	Contact for details

Quality Control

Our 4-5-Dibromoisothiozole-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.