Description

Cyclohexanone Tosylhydrazone CAS NO 4545-18-0 is a specialized organic compound belonging to the tosylhydrazone class, widely recognized as a versatile reagent and synthetic intermediate in advanced organic synthesis. Its primary value lies in its utility as a precursor for generating reactive carbene or diazo intermediates, enabling critical carbon-carbon and carbon-heteroatom bond-forming reactions. This high-purity chemical is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis of complex molecules, heterocycles, and novel materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly those requiring carbene insertion chemistry.
• Organic Synthesis Reagent: Employed in the Shapiro reaction and Bamford-Stevens reaction for the efficient generation of alkenes from carbonyl compounds, facilitating the construction of complex molecular architectures.
• Polymer & Material Science: Used as a precursor for functionalized monomers or cross-linking agents in the development of specialty polymers and advanced materials.
• Agrochemical Research: Serves as an intermediate in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Academic & Industrial R&D: A critical reagent for methodological development in synthetic organic chemistry, enabling new reaction pathways and catalysis studies.
• Fine Chemical Production: Utilized in the manufacture of dyes, fragrances, and other high-value specialty chemicals requiring precise synthetic transformations.

Basic Information

Product Name	Cyclohexanone Tosylhydrazone
CAS No.	4545-18-0
Molecular Formula	C₁₃H₁₈N₂O₂S
Molecular Weight	266.36 g/mol
Synonyms	Cyclohexanone p-Toluenesulfonylhydrazone; (Cyclohexylideneamino)(4-methylphenyl)sulfonamide; Tosylhydrazone of Cyclohexanone; Cyclohexanone tosyl hydrazone; p-Toluenesulfonylhydrazone of cyclohexanone; Cyclohexanone, tosylhydrazone; Cyclohexanone-4-toluenesulfonylhydrazone; Cyclohexanone tosylhydrazone reagent
EINECS	Contact for details

Quality Control

Our Cyclohexanone Tosylhydrazone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to quality ensures the material meets the stringent requirements for research and industrial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.