Description

1,2-Diphenylcyclobutane-3,4-Dicarboxylic Acid is a high-purity, functionalized cyclobutane derivative of significant interest in advanced organic synthesis. This compound serves as a versatile chiral building block and a key precursor for the development of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, advanced materials, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of constrained analogs and peptidomimetics.
• Ligand & Catalyst Precursor: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties.
• Academic & Industrial Research: A valuable tool for methodological studies in organic chemistry, including photocycloaddition reactions and stereoselective synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, dyes, and other high-value specialty chemicals.

Basic Information

Product Name	1,2-Diphenylcyclobutane-3,4-Dicarboxylic Acid
CAS No.	4482-52-4
Molecular Formula	C18H16O4
Molecular Weight	296.32 g/mol
Synonyms	1,2-Diphenylcyclobutane-3,4-dicarboxylic acid; 3,4-Dicarboxy-1,2-diphenylcyclobutane; 1,2-Diphenyl-3,4-cyclobutanedicarboxylic Acid; α-Truxillic Acid; Truxillic Acid; Diphenylcyclobutane Dicarboxylic Acid; 1,2-Diphenylcyclobutane-3,4-dicarboxylate; (1R,2S,3S,4R)-1,2-Diphenylcyclobutane-3,4-dicarboxylic acid
EINECS	Contact for details

Quality Control

Our 1,2-Diphenylcyclobutane-3,4-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.