Description

3-Carboxamidobenzoic Acid is a versatile benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a carboxylic acid and a carboxamide group, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting inflammation or metabolic disorders.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, where its aromatic core provides structural rigidity and sites for functionalization.
• Ligand and Chelator Preparation: Serves as a starting material for synthesizing specialized ligands used in catalysis or metal ion sequestration.
• Polymer Modification: Employed to introduce polar, hydrogen-bonding sites into polymer backbones to modify physical properties like solubility and thermal stability.
• Peptidomimetic Research: The carboxamidobenzoic moiety is utilized in the design of peptidomimetics and protease inhibitors.
• Dye and Pigment Intermediate: Acts as a building block for certain azo dyes and high-performance pigments.

Basic Information

Product Name	3-Carboxamidobenzoic Acid
CAS No.	4481-28-1
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	3-Aminocarbonylbenzoic Acid; Benzoic acid, 3-(aminocarbonyl)-; 3-Carbamoylbenzoic Acid; m-Carbamoylbenzoic Acid; Isophthalamic Acid; 3-Amidobenzoic Acid; 3-Carboxybenzamide; AI3-52022; NSC 403697
EINECS	Contact for details

Quality Control

Every batch of 3-Carboxamidobenzoic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We can supply material suitable for research and industrial applications, with specifications aligned with current Good Manufacturing Practice (cGMP) principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.