Description

2-Aminobenzamidine is a high-purity, bifunctional organic compound featuring both an aromatic amine and an amidine group, making it a versatile building block for chemical synthesis. Its primary value lies in its role as a key intermediate for the development of pharmaceutical compounds, particularly serine protease inhibitors. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis facilities requiring a reliable and high-quality source of this specialized reagent.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of drug candidates targeting serine proteases, such as thrombin and trypsin inhibitors.
• Biochemical Research: Used as a chemical tool or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: Serves as the core scaffold for designing and synthesizing novel enzyme inhibitors for therapeutic applications.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce the benzamidine functionality into more complex molecules.
• Chemical Biology Probes: Utilized in the development of activity-based probes for studying protease function in biological systems.

Basic Information

Product Name	2-Aminobenzamidine
CAS No.	4392-06-7
Molecular Formula	C7H9N3
Molecular Weight	135.16 g/mol
Synonyms	2-Aminobenzene carboximidamide; o-Aminobenzamidine; 1,2-Diaminobenzene-1-carboximidamide; Benzenecarboximidamide, 2-amino-; 2-Amino-benzenecarboximidamide; 2-Amino-benzamidine; 2-Amino-phenylamidine
EINECS	224-509-4

Quality Control

Our 2-Aminobenzamidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.