Description

[2R,(+)]-3,4-Dihydro-2α-(3,4,5-Trihydroxyphenyl)-2H-1-Benzopyran-3β,4α,7-Triol is a high-purity, stereochemically defined flavonoid derivative of significant interest in advanced research and development. This compound matters for its role as a key chiral intermediate and reference standard in the synthesis of complex natural products and bioactive molecules. It is primarily needed by pharmaceutical R&D teams, nutraceutical formulators, and academic researchers focused on polyphenol chemistry, antioxidant mechanisms, and glycosidase inhibition studies.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel therapeutic agents targeting metabolic and inflammatory pathways.
• Biochemical Research: Used as a high-purity reference standard in enzymatic assays and studies of flavonoid metabolism and bioavailability.
• Nutraceutical Development: Employed in the formulation and standardization of advanced dietary supplements with targeted antioxidant properties.
• Natural Product Synthesis: A key precursor in the semi-synthesis of complex flavan-3-ols and proanthocyanidins for structure-activity relationship (SAR) studies.
• Analytical Chemistry: Functions as an analytical standard for HPLC, LC-MS, and NMR method development and validation in quality control laboratories.

Basic Information

Product Name	[2R,(+)]-3,4-Dihydro-2α-(3,4,5-Trihydroxyphenyl)-2H-1-Benzopyran-3β,4α,7-Triol
CAS No.	4382-45-0
Molecular Formula	C₁₅H₁₄O₇
Molecular Weight	306.27 g/mol
Synonyms	(+)-Gallocatechin; 2R,3S-Gallocatechin; Gallocatechol; [2R-(2α,3β,4α)]-3,4-Dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,4,7-triol; 3,4,5,7-Tetrahydroxyflavan-3-ol; (2R,3S)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,4,7-triol
EINECS	Contact for details

Quality Control

Our [2R,(+)]-3,4-Dihydro-2α-(3,4,5-Trihydroxyphenyl)-2H-1-Benzopyran-3β,4α,7-Triol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent specifications for research and development use. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.