Description

5,7-Dihydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-6,8-Dimethoxy-4H-1-Benzopyran-4-One CAS NO 4281-28-1 is a specialized flavonoid derivative, a high-purity chemical building block of significant interest in advanced research and development. Its complex polyphenolic structure makes it a valuable reference standard and synthetic intermediate for investigating biological activity and material properties. This compound is primarily sought by R&D chemists and formulators in the pharmaceutical, nutraceutical, and fine chemical sectors.

Application

• Pharmaceutical Research: Serves as a key intermediate or reference standard in the synthesis and study of novel therapeutic agents, particularly those targeting oxidative stress and inflammation.
• Nutraceutical Development: Used in the research and formulation of advanced dietary supplements and functional food ingredients due to its polyphenolic nature.
• Biochemical Research: Acts as a precise tool in enzymatic studies, receptor binding assays, and as a probe for investigating flavonoid metabolism and bioavailability.
• Cosmeceutical Applications: Investigated for potential use in high-end skincare formulations for its antioxidant properties and ability to modulate skin cell responses.
• Analytical Chemistry: Employed as a certified reference material (CRM) for the calibration of instruments and validation of analytical methods (e.g., HPLC, LC-MS) in quality control laboratories.
• Organic Synthesis: Functions as a sophisticated starting material or intermediate for the synthesis of more complex, structurally related flavonoid analogs and novel chemical entities.

Basic Information

Product Name	5,7-Dihydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-6,8-Dimethoxy-4H-1-Benzopyran-4-One
CAS No.	4281-28-1
Molecular Formula	C₁₈H₁₆O₈
Molecular Weight	360.32 g/mol
Synonyms	5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-4H-chromen-4-one; 6,8-Dimethoxy-5,7,4'-trihydroxy-3'-methoxyflavone; 5,7,4'-Trihydroxy-6,8,3'-trimethoxyflavone; 3'-Methoxy-6,8-dimethoxy-5,7,4'-trihydroxyflavone; 5,7,4'-Trihydroxy-3'-methoxy-6,8-dimethoxyflavone; Flavonoid Derivative 4281-28-1; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-
EINECS	Contact for details

Quality Control

Our 5,7-Dihydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-6,8-Dimethoxy-4H-1-Benzopyran-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) documenting identity, purity, and all relevant test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.