Description

Monothiolphenyl Malonate is a specialized organosulfur compound that serves as a versatile intermediate and building block in advanced chemical synthesis. Its unique structure, featuring both a thiol and a malonate ester group, makes it a valuable reagent for constructing complex molecules and functional materials. This product is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and polymer industries seeking to introduce specific sulfur-containing functionalities.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring thioether or sulfur-heterocycle motifs.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the malonate-thiol structure imparts specific biological activity.
• Polymer Modification: Acts as a chain transfer agent (CTA) or cross-linking monomer in the synthesis of specialty polymers and resins to modify physical properties.
• Ligand Precursor: Serves as a starting material for the preparation of chelating ligands used in catalysis and metal complexation.
• Organic Synthesis Reagent: Employed in Michael addition reactions, nucleophilic substitutions, and other C-S bond-forming transformations in fine chemical production.
• Material Science Research: Investigated for use in the development of self-assembled monolayers (SAMs) and advanced organic electronic materials.

Basic Information

Product Name	Monothiolphenyl Malonate
CAS No.	4279-77-0
Molecular Formula	C11H10O4S
Molecular Weight	238.26 g/mol
Synonyms	Phenyl Mercaptomalonate; Phenyl Thiomalonate; Monothiomalic Acid Phenyl Ester; 2-Mercapto-2-phenylmalonic Acid Dimethyl Ester (common misnomer); (Phenylthio)malonic Acid Ester; 4279-77-0; NSC 163082; Phenyl (mercapto)propanedioate
EINECS	Contact for details

Quality Control

Our Monothiolphenyl Malonate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP for pharmaceutical intermediates and ISO standards for industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be sensitive to moisture and oxidation; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.