Description

4,4-Dichloro-1-Butene is a versatile chlorinated alkene intermediate with significant utility in organic synthesis. Its bifunctional structure, featuring both a reactive alkene and chlorinated termini, makes it a valuable building block for constructing more complex molecules. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for use in cross-coupling reactions, cyclizations, and as a precursor for various functionalized derivatives.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) and nucleophilic substitution reactions.
• Ligand & Catalyst Preparation: Useful for synthesizing novel ligands and organometallic catalysts.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries in R&D laboratories.

Basic Information

Product Name	4,4-Dichloro-1-Butene
CAS No.	4279-19-0
Molecular Formula	C4H6Cl2
Molecular Weight	124.99 g/mol
Synonyms	1-Butene, 4,4-dichloro-; 4,4-Dichlorobut-1-ene; 4,4-Dichloro-1-butylene; 1,1-Dichloro-3-butene; 4,4-Dichlorobutene-1; But-1-ene-4,4-dichloride
EINECS	224-269-6

Quality Control

Our 4,4-Dichloro-1-Butene is manufactured under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and highly volatile compound, keep away from heat, sparks, open flames, and incompatible materials. Use appropriate grounding and bonding procedures during handling and transfer.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.15 - 1.20 g/mL
Refractive Index (n20D)	1.460 - 1.470

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.