Description

(-)-p-Mentha-1,5-Diene CAS NO 4221-98-1 is a high-purity, optically active monoterpene hydrocarbon, a key chiral intermediate and flavor/fragrance component. Its specific stereochemistry makes it a valuable building block for the synthesis of fine chemicals and natural product analogs, offering precise control over the sensory and biological properties of the final product. This compound is essential for manufacturers in the flavor & fragrance, pharmaceutical, and agrochemical industries seeking to develop or produce enantiomerically pure substances.

Application

• Flavor & Fragrance (F&F) Industry: A key chiral ingredient and starting material for the synthesis of high-value minty, citrus, and herbal aroma chemicals and natural flavor compounds.
• Pharmaceutical Intermediates: Serves as a versatile chiral synthon in the research and production of active pharmaceutical ingredients (APIs) and other bioactive molecules.
• Agrochemical Synthesis: Used as a precursor in the development of chiral pesticides, herbicides, and other specialty agrochemicals.
• Chemical Research & Development: A valuable standard and reagent in organic synthesis, catalysis studies, and stereochemistry research.
• Natural Product Chemistry: Employed in the semi-synthesis or total synthesis of complex terpenoids and other natural products.

Basic Information

Product Name	(-)-p-Mentha-1,5-Diene
CAS No.	4221-98-1
Molecular Formula	C10H16
Molecular Weight	136.23 g/mol
Synonyms	(-)-α-Phellandrene; (4S)-4-Isopropyl-1-methyl-1,3-cyclohexadiene; L-α-Phellandrene; (S)-(-)-α-Phellandrene; 1,3-Cyclohexadiene, 4-(1-methylethyl)-, (S)-; p-Mentha-1,5-diene, (S)-(-)-; (S)-4-Isopropyl-1-methyl-1,3-cyclohexadiene
EINECS	224-175-3

Quality Control

Our (-)-p-Mentha-1,5-Diene is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for advanced synthesis and F&F applications. A detailed Certificate of Analysis (COA) specifying identity, purity, optical rotation, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 95.0%
Chiral Purity (GC/HPLC)	≥ 98.0% ee (S)-enantiomer
Optical Rotation [α]D20	-150° to -170° (c=1 in CHCl3)
Refractive Index nD20	1.470 - 1.480
Specific Gravity (20°C)	0.830 - 0.850

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.