Description

o-Methylserine is a non-proteinogenic amino acid derivative of serine, featuring a methyl group substitution on the hydroxyl side chain. This structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is particularly sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, peptide mimetics, and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in enzymatic studies, metabolic pathway analysis, and as a precursor for labeled compounds in proteomics and metabolomics.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and plant growth regulators with specific chiral activity.
• Peptide Chemistry: Incorporated into custom peptides to study structure-activity relationships (SAR) and to create peptides with enhanced stability or novel properties.
• Ligand and Catalyst Development: Utilized in the preparation of chiral ligands for asymmetric catalysis and metal complexes.
• Cosmetic & Personal Care Actives: Potential intermediate for synthesizing specialty ingredients with skin-conditioning or moisturizing properties.

Basic Information

Product Name	o-Methylserine
CAS No.	4219-94-7
Molecular Formula	C4H9NO3
Molecular Weight	119.12 g/mol
Synonyms	O-Methyl-L-serine; (S)-2-Amino-3-methoxypropanoic acid; 3-Methoxy-L-alanine; L-O-Methylserine; 2-Amino-3-methoxypropionic acid; NSC 163049; H-Ser(OMe)-OH
EINECS	224-163-5

Quality Control

Our o-Methylserine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.