Description

[1R-(1Alpha,4Beta,6Beta)]-4,7,7-Trimethylbicyclo[4.1.0]Heptan-3-One is a high-purity, stereochemically defined bicyclic ketone, a key chiral intermediate in advanced organic synthesis. Its rigid, functionalized structure makes it a valuable building block for creating complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), fragrances, and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Serves as a versatile building block in the production of complex, high-value specialty chemicals.
• Fragrance & Flavor Chemistry: Used in the research and development of unique, musky, or woody scent molecules due to its bicyclic framework.
• Agrochemical Research: Employed as a precursor in creating advanced, stereospecific pesticides and herbicides.
• Material Science: Investigated as a monomer or cross-linking agent for producing polymers with specific thermal or mechanical properties.
• Catalyst & Ligand Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Item	Detail
Product Name	[1R-(1Alpha,4Beta,6Beta)]-4,7,7-Trimethylbicyclo[4.1.0]Heptan-3-One
CAS No.	4176-01-6
Molecular Formula	C10H16O
Molecular Weight	152.23 g/mol
Synonyms	(1R,4R,6R)-4,7,7-Trimethylbicyclo[4.1.0]heptan-3-one; (-)-3-Thujone; (1R,4R,6R)-3-Thujanone; α-Thujone (specific stereoisomer); 3-Thujanone; Sabinone; Bicyclo[4.1.0]heptan-3-one, 4,7,7-trimethyl-, (1R,4R,6R)-
EINECS	Contact for details

Quality Control

Every batch of [1R-(1Alpha,4Beta,6Beta)]-4,7,7-Trimethylbicyclo[4.1.0]Heptan-3-One is manufactured under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with each shipment to guarantee it meets your precise research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.