Description

4-Estren-6Beta,17Beta-Diol-3-One is a high-purity steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of more complex steroidal drugs and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in the development of hormone therapies and other specialized medicinal compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of steroidal active pharmaceutical ingredients (APIs) and prohormones.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Hormone Analog Synthesis: Serves as a starting material for the development of novel androgen and estrogen analogs with potential therapeutic applications.
• Reference Standard: Employed as an analytical standard in quality control (QC) and method development for HPLC, GC-MS, or other chromatographic techniques.
• Biochemical Research: Utilized in enzymatic studies and metabolic pathway investigations related to steroid hormones.
• Fine Chemical Production: Integrated into custom synthesis projects for producing specialized, high-value steroid derivatives.

Basic Information

Product Name	4-Estren-6Beta,17Beta-Diol-3-One
CAS No.	4146-29-6
Molecular Formula	C19H28O2
Molecular Weight	288.43 g/mol
Synonyms	6β,17β-Dihydroxy-4-estren-3-one; 4-Estren-3-one-6β,17β-diol; 6β,17β-Dihydroxyestr-4-en-3-one; 17β-Hydroxy-6β-hydroxyestr-4-en-3-one; Estr-4-ene-3,6,17-triol, (6β,17β)- (9CI); 6β-Hydroxy-19-nortestosterone; 6β,17β-Dihydroxy-19-nor-4-androsten-3-one
EINECS	Contact for details

Quality Control

Our 4-Estren-6Beta,17Beta-Diol-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by HPLC, to ensure it meets high-purity standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.