Description

1,1,2,2-Tetramethylcyclopropane is a highly specialized, strained-ring hydrocarbon with a unique sterically hindered cyclopropane structure. This compound serves as a valuable and versatile chemical intermediate and building block in advanced organic synthesis, particularly for introducing rigid, bulky substituents. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical R&D laboratories for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules, especially those requiring rigid, three-dimensional scaffolds to modulate biological activity and selectivity.
• Agrochemical Synthesis: Serves as a key building block for creating novel pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create sterically demanding ligands for transition metal catalysts.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal and mechanical properties due to its strained ring.
• Organic Synthesis Reagent: Acts as a precursor for cyclopropanation reactions and the construction of complex polycyclic frameworks in academic and industrial research.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing unique musk or woody odorants with high stability.

Basic Information

Product Name	1,1,2,2-Tetramethylcyclopropane
CAS No.	4127-47-3
Molecular Formula	C7H14
Molecular Weight	98.19 g/mol
Synonyms	1,1,2,2-Tetramethylcyclopropane; Tetramethylcyclopropane; NSC 66425; Cyclopropane, 1,1,2,2-tetramethyl-; 1,1,2,2-Tetramethylcyclopropan; 4127-47-3 (CAS); Tetramethyl cyclopropane
EINECS	223-933-6

Quality Control

Every batch of 1,1,2,2-Tetramethylcyclopropane is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical synthetic applications. Certificates of Analysis (COA) detailing specifications such as assay (by GC), identity (IR/GC-MS), and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids and oxidizers. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0% Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.