Description

p-Toluenesulfonic Anhydride is a versatile and highly reactive organic intermediate, primarily used as a powerful sulfonating and dehydrating agent. Its reactivity makes it a critical reagent for constructing complex molecular architectures in fine chemical synthesis. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors seeking efficient and selective synthesis pathways.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent in the production of active pharmaceutical ingredients (APIs), particularly for introducing sulfonyl groups or facilitating esterification and condensation reactions under mild conditions.
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and plant growth regulators where sulfonamide or sulfonate ester functionalities are required.
• Polymer & Resin Chemistry: Acts as a curing agent or cross-linking catalyst in the production of specialty polymers, epoxy resins, and coatings.
• Dye & Pigment Production: Employed as a sulfonating agent in the manufacture of sulfonated dyes and organic pigments to enhance solubility and color properties.
• Organic Synthesis Reagent: A valuable tool in academic and industrial research for dehydration reactions, the synthesis of sulfonic esters, and as a catalyst in various organic transformations.
• Fine Chemical Production: Integral to the manufacture of flavors, fragrances, and other high-value specialty chemicals requiring precise sulfonation steps.

Basic Information

Item	Details
Product Name	p-Toluenesulfonic Anhydride
CAS No.	4124-41-8
Molecular Formula	C14H14O5S2
Molecular Weight	326.39 g/mol
Synonyms	4-Methylbenzenesulfonic Anhydride; Tosic Anhydride; Tosyl Anhydride; p-Toluenesulphonic Anhydride; p-Tosyl Anhydride; Toluenesulfonic Acid Anhydride; Benzenesulfonic Acid, 4-methyl-, anhydride; TSAN
EINECS	223-925-3

Quality Control

Our p-Toluenesulfonic Anhydride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay, impurity profiling, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your technical requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases, strong oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	96 - 100 °C
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.