Description

n-Sulfinyl-p-Toluenesulfonamide is a specialized sulfinylating reagent used in organic synthesis. This compound is valued for its role in introducing the sulfinyl group, a key functional moiety in the development of pharmaceuticals and fine chemicals. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries. Its reactivity makes it a critical building block for constructing complex sulfur-containing molecules.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of sulfonamide-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that contain sulfinyl or sulfonamide groups.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring precise sulfinylation.
• Academic & Industrial Research: Serves as a versatile building block in methodological development and novel compound library synthesis.
• Peptide Modification: Potential use in the selective modification of peptides and proteins to study structure-activity relationships.

Basic Information

Product Name	n-Sulfinyl-p-Toluenesulfonamide
CAS No.	4104-47-6
Molecular Formula	C7H7NO3S2
Molecular Weight	217.26 g/mol
Synonyms	N-Sulfinyltosylamide; p-Toluenesulfonylsulfinylamide; Tosylsulfinylamide; N-(Sulfinyl)-4-methylbenzenesulfonamide; 4-Methyl-N-sulfinylbenzenesulfonamide; Benzenesulfonamide, N-sulfinyl-4-methyl-; TSIA; N-Sulfinyl-p-toluenesulfonamide
EINECS	Contact for details

Quality Control

Our n-Sulfinyl-p-Toluenesulfonamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee reproducible performance and supply chain reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.