Description

4,4A,5,6,7,8-Hexahydro-4A,8-Dimethylnaphthalen-2(3H)-One is a specialized hydrogenated naphthalenone derivative, valued for its unique structural framework that serves as a versatile intermediate in advanced organic synthesis. Its partially saturated ring system and ketone functionality make it a critical building block for creating complex molecules with specific stereochemistry and properties. This compound is essential for R&D and production in the pharmaceutical and fine chemical industries, where it is used to develop active ingredients, fragrances, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel therapeutic agents, including steroids and other bioactive molecules.
• Fragrance & Flavor Chemistry: Serves as a precursor in the creation of complex musk-like or woody aroma chemicals for perfumery and flavoring applications.
• Fine Chemical Synthesis: Used as a versatile building block in the multi-step synthesis of complex organic compounds for agrochemicals and material science.
• Organic Research & Development: Employed in academic and industrial R&D labs for methodological studies in hydrogenation, cyclization, and asymmetric synthesis.
• Specialty Polymer Modifiers: Acts as a monomer or functional additive in the development of specialty polymers with tailored thermal or optical properties.

Basic Information

Product Name	4,4A,5,6,7,8-Hexahydro-4A,8-Dimethylnaphthalen-2(3H)-One
CAS No.	4071-63-0
Molecular Formula	C₁₂H₁₈O
Molecular Weight	178.27 g/mol
Synonyms	4a,8-Dimethyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one; 4a,8-Dimethyl-4,4a,5,6,7,8-hexahydro-2-naphthalenone; 2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-4a,8-dimethyl-; 4a,8-Dimethyl-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone; 4a,8-Dimethyl-1,2,3,4,4a,5,6,7-octahydronaphthalen-2-one; Dihydrocadalene derivative; Hexahydronaphthalenone derivative
EINECS	Contact for details

Quality Control

Our 4,4A,5,6,7,8-Hexahydro-4A,8-Dimethylnaphthalen-2(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.