Description

4-Oxo-4-[(Tributylstannyl)Oxy]But-2-Enoic Acid is a specialized organotin reagent featuring a reactive β-keto acid moiety. This compound is valued for its dual functionality, serving as a versatile building block in advanced organic synthesis and metal-mediated coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring tin-mediated Stille coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate organotin functional groups.
• Polymer Chemistry: Acts as a monomer or chain-transfer agent in the development of specialty polymers and functional materials.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing novel organotin catalysts and ligands used in homogeneous catalysis.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing carbon-carbon bonds and introducing the tributylstannyl group into target molecules.
• Material Science Research: Investigated for use in creating tin-containing hybrid materials and surface modifiers.

Basic Information

Product Name	4-Oxo-4-[(Tributylstannyl)Oxy]But-2-Enoic Acid
CAS No.	4027-18-3
Molecular Formula	C16H30O4Sn
Molecular Weight	405.11 g/mol
Synonyms	2-Butenoic acid, 4-oxo-4-[(tributylstannyl)oxy]-; 4-(Tributylstannyloxy)-4-oxobut-2-enoic acid; (E)-4-Oxo-4-(tributylstannyloxy)but-2-enoic acid; Tributylstannyl 4-oxobut-2-enoate; Tributyltin 4-oxo-2-butenoate; Keto acid tributyltin ester; Organotin β-keto acid ester
EINECS	Contact for details

Quality Control

Our production of 4-Oxo-4-[(Tributylstannyl)Oxy]But-2-Enoic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized by NMR (1H, 13C, 119Sn), FT-IR, and HPLC analysis to confirm identity and purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C. Keep away from strong bases and incompatible materials such as oxidizing agents. The container must be kept tightly closed in a well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	28.5 - 30.0 %
Solubility	Soluble in common organic solvents (e.g., THF, DCM, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.