Description

N''-Acetyl-2-Chloroacetohydrazide is a versatile organic intermediate featuring both acetyl and chloroacetyl functional groups on a hydrazide core. This unique structure makes it a valuable building block for the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various heterocyclic scaffolds, including pyrazoles, triazoles, and oxadiazoles, which are core structures in many drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its reactive sites for structural diversification.
• Chemical Research & Development: Serves as a versatile reagent in organic synthesis for introducing the N-acetylhydrazide moiety or for further functionalization via the reactive chlorine atom.
• Coordination Chemistry: Can act as a ligand or precursor for metal-organic frameworks (MOFs) and catalysts due to its nitrogen and oxygen donor atoms.
• Polymer Modification: Potential use as a cross-linking agent or functional monomer for specialty polymers.

Basic Information

Product Name	N''-Acetyl-2-Chloroacetohydrazide
CAS No.	4002-21-5
Molecular Formula	C4H7ClN2O2
Molecular Weight	150.56 g/mol
Synonyms	2-Chloro-N'-(acetyl)acetohydrazide; 2-Chloroacetohydrazide N-acetyl derivative; Acetic acid, 2-chloro-, 2-acetylhydrazide; N-Acetyl-2-chloroacetohydrazide; 2-Chloroacetic acid acetylhydrazide; Chloroacetic acid acetylhydrazide; N'-Acetylchloroacetohydrazide; (2-Chloroacetyl)acetohydrazide
EINECS	Contact for details

Quality Control

Our N''-Acetyl-2-Chloroacetohydrazide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The product may be hygroscopic; handle in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.