Description

4-Chloromandelic Acid is a versatile chiral organic compound that serves as a key intermediate in fine chemical synthesis. Its value lies in its utility for constructing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. This product is essential for research and development chemists, process engineers, and manufacturers involved in producing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of chiral drugs, including certain β-blockers and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where specific stereochemistry is required for efficacy.
• Chiral Resolving Agent: Employed for the separation of racemic mixtures of amines and other basic compounds due to its acidic and chiral nature.
• Organic Synthesis Research: A valuable starting material or intermediate in academic and industrial research for exploring new synthetic methodologies.
• Ligand Precursor: Can be utilized in the preparation of chiral ligands for asymmetric catalysis.
• Fine Chemical Production: Serves as an intermediate in the manufacture of various specialty and performance chemicals.

Basic Information

Product Name	4-Chloromandelic Acid
CAS No.	492-86-4
Molecular Formula	C8H7ClO3
Molecular Weight	186.59 g/mol
Synonyms	(4-Chlorophenyl)(hydroxy)acetic acid; p-Chloromandelic Acid; 4-Chloro-α-hydroxybenzenacetic acid; DL-4-Chloromandelic Acid; (±)-4-Chloromandelic Acid; (RS)-4-Chloromandelic Acid; Mandelic acid, 4-chloro-; Benzenacetic acid, α-hydroxy-4-chloro-
EINECS	207-770-5

Quality Control

Our 4-Chloromandelic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Optical Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.