Description

2,3,4,5-Tetramethylphenol is a high-purity, multi-methylated phenolic compound with the CAS registry number 488-70-0. This specialty chemical serves as a versatile intermediate and building block in advanced organic synthesis, valued for its sterically hindered phenolic structure. It is essential for manufacturers and R&D facilities in the pharmaceutical, agrochemical, and polymer industries seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring hindered phenol moieties for antioxidant or stabilizing activity.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where its methyl-substituted structure imparts specific biological activity and stability.
• Polymer Additive Precursor: Serves as a starting material for manufacturing specialized antioxidants and light stabilizers (HALS - Hindered Amine Light Stabilizers) for plastics and synthetic fibers.
• Fine Chemical Synthesis: Employed in organic laboratories for the preparation of ligands, catalysts, and other functional materials due to its predictable reactivity and steric profile.
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of certain high-performance colorants and imaging chemicals.
• Research & Development: A valuable reference standard and reagent in chemical research for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	2,3,4,5-Tetramethylphenol
CAS No.	488-70-0
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	2,3,4,5-Tetramethylphenol; Phenol, 2,3,4,5-tetramethyl-; 2,3,4,5-Tetramethyl-1-hydroxybenzene; Durenol; Tetramethylhydroxybenzene; 1-Hydroxy-2,3,4,5-tetramethylbenzene; NSC 403697
EINECS	207-675-6

Quality Control

Our 2,3,4,5-Tetramethylphenol is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support compliance with global regulatory frameworks including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon blanket). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	112 - 116 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.