Description

(3R)-8-Hydroxy-3-Methyl-Isochroman-1-One CAS NO 480-33-1 is a high-purity chiral isochromanone derivative, a key building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable intermediate for creating complex molecules with specific biological activity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structural motif can contribute to specific biological targeting.
• Fine Chemical Production: Serves as a specialized precursor in the synthesis of flavors, fragrances, and other high-value fine chemicals requiring precise stereochemical control.
• Academic & Industrial Research: Employed in chemical research for methodological studies in asymmetric synthesis and as a reference standard for analytical purposes.
• Material Science Precursor: Potential use in the development of novel organic materials and ligands for catalytic systems.

Basic Information

Product Name	(3R)-8-Hydroxy-3-Methyl-Isochroman-1-One
CAS No.	480-33-1
Molecular Formula	C10H10O3
Molecular Weight	178.18 g/mol
Synonyms	(R)-8-Hydroxy-3-methylisochroman-1-one; (3R)-8-Hydroxy-3-methyl-1H-2-benzopyran-1-one; 8-Hydroxy-3-methylisochroman-1-one (enantiomer); (R)-3-Methyl-8-hydroxyisochroman-1-one; 1(2H)-Isochromenone, 8-hydroxy-3-methyl-, (3R)-; 480-33-1; (R)-form of 8-Hydroxy-3-methylisochroman-1-one
EINECS	Contact for details

Quality Control

Our (3R)-8-Hydroxy-3-Methyl-Isochroman-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for research and production use. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.