Description

Rhein CAS NO 478-43-3 is a naturally occurring anthraquinone derivative, recognized for its significant biological and pharmacological activities. This compound is a key active ingredient and a valuable reference standard in the development of therapeutic and nutraceutical products. It is essential for research and manufacturing in the pharmaceutical, cosmetic, and herbal supplement industries, where precise quality and reliable sourcing are paramount.

Application

• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of anti-inflammatory and hepatoprotective drugs.
• Reference Standards: Used as a high-purity analytical standard in quality control laboratories for HPLC and TLC methods.
• Natural Product Research: A vital compound for studying the mechanisms of traditional herbal medicines, particularly those derived from rhubarb and senna.
• Cosmetic Actives: Incorporated into skincare formulations for its potential antioxidant and anti-aging properties.
• Dietary Supplements: Utilized as a standardized extract component in nutraceuticals targeting digestive and metabolic health.
• Biochemical Research: Employed in in-vitro studies to investigate cellular signaling pathways related to inflammation and fibrosis.

Basic Information

Product Name	Rhein
CAS No.	478-43-3
Molecular Formula	C15H8O6
Molecular Weight	284.22 g/mol
Synonyms	Rheic Acid; 4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic Acid; Cassic Acid; Monorhein; Rhubarb Yellow; NSC 38698; 1,8-Dihydroxy-3-carboxyanthraquinone
EINECS	207-521-7

Quality Control

Our Rhein is produced under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and UV spectroscopy, to ensure it meets the stringent requirements for research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.