Description

Obtusifolin is a bioactive natural product and a key marker compound derived from the *Cassia obtusifolia* (Sicklepod) plant. This compound is of significant interest for its role in quality control and standardization within the herbal medicine and nutraceutical sectors. It serves as a critical reference standard for analytical laboratories and manufacturers requiring precise quantification in botanical extracts. Industries involved in pharmaceutical research, dietary supplement production, and phytochemical analysis rely on high-purity Obtusifolin to ensure product efficacy and regulatory compliance.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and assay of related herbal products in pharmacopoeial testing (e.g., USP, EP).
• Herbal Extract Standardization: Acts as a primary marker compound for the quality control and batch-to-batch consistency of *Cassia obtusifolia* (Jue Ming Zi) extracts.
• Biomedical Research: Employed in preclinical studies to investigate potential biological activities, including anti-inflammatory, neuroprotective, and hepatoprotective effects.
• Nutraceutical Manufacturing: Utilized in the formulation and quality assurance of dietary supplements where standardized anthraquinone content is specified.
• Analytical Method Development: Serves as a critical component in developing and validating HPLC, UPLC, and LC-MS methods for natural product analysis.

Basic Information

Product Name	Obtusifolin
CAS No.	477-85-0
Molecular Formula	C17H14O6
Molecular Weight	314.29 g/mol
Synonyms	1,8-Dihydroxy-3-methyl-6-methoxy-9,10-anthraquinone; 1,8-Dihydroxy-3-methyl-6-methoxyanthraquinone; Cassiaside B aglycone; 6-Methoxy-1,8-dihydroxy-3-methylanthraquinone; Aurantio-obtusin; 2-Methyl-4,5-dihydroxy-7-methoxy-9,10-anthracenedione
EINECS	Contact for details

Quality Control

Our Obtusifolin is produced under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substance analysis, to meet the stringent requirements for reference standard applications. A detailed Certificate of Analysis (COA) providing identity, purity, and chromatographic data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.