Description

Damnacanthal CAS NO 477-84-9 is a bioactive anthraquinone compound primarily isolated from the roots of the *Morinda citrifolia* (Noni) plant. This compound is of significant commercial interest due to its potent biological activities, particularly its role as a selective inhibitor of tyrosine kinases. It is a critical intermediate and reference standard for research and development in the pharmaceutical and biotechnology sectors, targeting applications in oncology and cell signaling studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of tyrosine kinase inhibitor therapies.
• Oncology Research: Used in preclinical studies to investigate mechanisms of cell proliferation and apoptosis, aiding in the discovery of novel anti-cancer agents.
• Biochemical Assays: Employed as a selective inhibitor in enzymatic assays to study signal transduction pathways involving kinases like Lck and Src.
• Natural Product Standardization: Acts as a marker compound for the quality control and standardization of herbal extracts, particularly those derived from Noni (*Morinda citrifolia*).
• Academic & Contract Research: Utilized in university and CRO laboratories for fundamental research in medicinal chemistry and pharmacology.

Basic Information

Product Name	Damnacanthal
CAS No.	477-84-9
Molecular Formula	C16H10O5
Molecular Weight	282.25 g/mol
Synonyms	3-Hydroxy-1-methoxy-2-methyl-9,10-anthraquinone; 1-Methoxy-2-methyl-3-hydroxy-9,10-anthraquinone; 1-Methoxy-2-methylanthraquinone-3-ol; Noni extract anthraquinone; Morindone derivative
EINECS	Contact for details

Quality Control

Our Damnacanthal is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (IR, NMR, MS) for structural confirmation, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.