Description

(1S,3Aα,8Aα)-Decahydro-4,8,8-Trimethyl-1β,4β-Azulenedicarboxylic Acid is a high-purity, functionalized azulene derivative, a bicyclic sesquiterpenoid compound of significant interest in advanced organic synthesis. Its unique fused ring structure and dual carboxylic acid functionality make it a valuable chiral building block for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries seeking to develop novel active ingredients, chiral catalysts, or specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for anti-inflammatory or anti-cancer applications.
• Fine Chemical Synthesis: Used as a sophisticated building block for constructing complex natural product analogs and specialty organic compounds.
• Catalyst & Ligand Development: The carboxylic acid groups and rigid chiral framework are utilized to develop novel asymmetric catalysts and chiral ligands for enantioselective reactions.
• Material Science Research: Investigated as a monomer or functional additive for creating polymers with unique optical or electronic properties derived from the azulene core.
• Fragrance & Flavor Chemistry: Acts as an intermediate in the synthesis of high-value sesquiterpenoid-based aroma chemicals.
• Academic & R&D: A critical reagent for methodological studies in organic chemistry, including cycloaddition reactions and stereochemical investigations.

Basic Information

Product Name	(1S,3Aα,8Aα)-Decahydro-4,8,8-Trimethyl-1β,4β-Azulenedicarboxylic Acid
CAS No.	474-94-2
Molecular Formula	C₁₅H₂₂O₄
Molecular Weight	266.33 g/mol
Synonyms	1,4-Azulenedicarboxylic acid, decahydro-4,8,8-trimethyl-, (1S,3aα,8aα)-; (-)-Guai-1(10),11-diene-12,6-olide-8-carboxylic acid (derivative); Dihydrocostunolide-8-carboxylic acid; Azulene-1,4-dicarboxylic acid derivative; (1S,3aS,8aS)-Decahydro-4,8,8-trimethyl-1,4-azulenedicarboxylic acid; Guaianediolide carboxylic acid; Aromatic sesquiterpenoid dicarboxylic acid.
EINECS	207-479-0

Quality Control

Our (1S,3Aα,8Aα)-Decahydro-4,8,8-Trimethyl-1β,4β-Azulenedicarboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.