Description

Endo-3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxylic acid is a specialized bicyclic carboxylic acid derivative, valued for its unique sterically hindered structure. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, structurally defined intermediates for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of prostaglandin analogs and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bicyclic framework contributes to biological activity.
• Fine Chemical Production: Serves as a versatile building block for creating complex fragrance compounds, flavors, and other high-value specialty chemicals.
• Asymmetric Catalysis & Ligand Design: Employed in the development of novel chiral ligands and catalysts for stereoselective synthesis.
• Material Science Research: Investigated as a monomer or additive for synthesizing polymers with specific thermal or mechanical properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including cycloaddition reactions and stereochemistry research.

Basic Information

Product Name	Endo-3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxylic Acid
CAS No.	474-10-2
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	Endo-3,3-Dimethyl-2-norbornanecarboxylic Acid; Endo-3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxylic Acid; 3,3-Dimethyl-2-norbornanecarboxylic Acid (endo-); 2-Norbornanecarboxylic acid, 3,3-dimethyl-, endo-; Bicyclo[2.2.1]heptane-2-carboxylic acid, 3,3-dimethyl-, endo-; 3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxylic Acid (endo-); Contact for additional trade names or abbreviations.
EINECS	207-466-4

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity chemical intermediates. We provide comprehensive analytical data, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports the needs of cGMP-compliant manufacturing where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.