Description

Cyclobutaneacetic Acid, 3-Carboxy-2,2-Dimethyl- is a high-purity, functionalized cyclobutane derivative serving as a critical advanced intermediate in organic synthesis. Its unique bicyclic structure with multiple carboxyl groups makes it a valuable building block for constructing complex molecular architectures with specific steric and electronic properties. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those requiring rigid, constrained ring systems.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators that leverage its unique carboxy-substituted cyclobutane core.
• Material Science: Serves as a monomer or cross-linking agent for creating polymers with tailored thermal and mechanical properties.
• Ligand Synthesis: Utilized in organic and organometallic chemistry to prepare sophisticated chelating ligands for catalysis.
• Chemical Biology Probes: Acts as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Fine Chemical Production: An intermediate in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Cyclobutaneacetic Acid, 3-Carboxy-2,2-Dimethyl-
CAS No.	473-73-4
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	3-Carboxy-2,2-dimethylcyclobutaneacetic acid; 2,2-Dimethyl-3-carboxycyclobutaneacetic acid; 1,1-Cyclobutanedicarboxylic acid, 2,2-dimethyl-; 2,2-Dimethylcyclobutane-1,3-diacetic acid; Cyclobutane-1,3-diacetic acid, 2,2-dimethyl-; NSC 163045; 2,2-Dimethyl-1,3-cyclobutanedicarboxylic acid (common name)
EINECS	207-473-5

Quality Control

Our Cyclobutaneacetic Acid, 3-Carboxy-2,2-Dimethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment supports applications in cGMP and ISO-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.