Description

[4Ar-(4Aalpha,6Abeta,10Aalpha,10Bbeta)]-Dodecahydro-4A,7,7,10A-Tetramethyl-3H-Naphth[2,1-B]Pyran-3-One CAS NO 468-84-8 is a high-purity, complex organic compound belonging to the class of decalin-fused pyranones. This specialized chemical is valued for its unique stereochemistry and structural framework, making it a critical advanced intermediate in sophisticated organic synthesis. It is primarily sought by pharmaceutical R&D and fine chemical sectors for the development of novel active compounds and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates, particularly in steroid-like or terpenoid-based therapeutic research.
• Organic Synthesis Research: Used as a sophisticated precursor for constructing complex polycyclic frameworks in academic and industrial research laboratories.
• Fragrance & Flavor Chemistry: Acts as a potential intermediate for synthesizing high-value, structurally unique aroma chemicals due to its complex decalin core.
• Material Science: Investigated for the development of specialty polymers or liquid crystals where specific stereochemistry and rigidity are required.
• Agrochemical Research: Utilized in the research and development of novel, high-specificity active ingredients for crop protection.

Basic Information

Product Name	[4Ar-(4Aalpha,6Abeta,10Aalpha,10Bbeta)]-Dodecahydro-4A,7,7,10A-Tetramethyl-3H-Naphth[2,1-B]Pyran-3-One
CAS No.	468-84-8
Molecular Formula	C19H30O2
Molecular Weight	290.44 g/mol
Synonyms	4Ar-(4aα,6aβ,10aα,10bβ)-Dodecahydro-4a,7,7,10a-tetramethyl-3H-naphtho[2,1-b]pyran-3-one; Ambrox; Ambroxide; (-)-Ambrox; (3aR,5aS,9aS,9bR)-Dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan; 3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan; Ambroxan; Fixateur 404.
EINECS	207-428-3

Quality Control

Our production of [4Ar-(4Aalpha,6Abeta,10Aalpha,10Bbeta)]-Dodecahydro-4A,7,7,10A-Tetramethyl-3H-Naphth[2,1-B]Pyran-3-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral GC/HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.