Description

Marrubiin CAS NO 465-92-9 is a bitter diterpenoid lactone, a key bioactive constituent primarily extracted from the herb *Marrubium vulgare* (White Horehound). This compound is valued for its distinct pharmacological properties and serves as a critical reference standard and active ingredient. It is essential for manufacturers and researchers in the pharmaceutical, nutraceutical, and herbal extract industries seeking to develop or standardize products related to respiratory health, digestion, and metabolic function.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for the identification, assay, and quality control of herbal medicines and dietary supplements containing White Horehound extract.
• Nutraceutical Formulations: Incorporated as a key active marker in herbal supplements targeting respiratory wellness, digestive aid, and appetite stimulation.
• Herbal Extract Standardization: Serves as a target compound for the standardization and potency verification of crude *Marrubium vulgare* extracts to ensure consistent bioactivity.
• Research & Development: Utilized in preclinical and pharmacological studies to investigate its potential effects on channels, inflammation, and metabolic pathways.
• Flavoring Agent Production: Employed in the development of bittering agents for specialty food products, beverages, and liqueurs.

Basic Information

Product Name	Marrubiin
CAS No.	465-92-9
Molecular Formula	C20H28O4
Molecular Weight	332.43 g/mol
Synonyms	Marrubenol; (-)-Marrubiin; Marrubiine; (4aR,5S,6aS,9S,10aR,10bS)-5-(2-Furanyl)decahydro-5,6a,9,10b-tetramethyl-1H-naphtho[2,1-c]pyran-1-one; L,5a-Epoxy-6b,10b,14-trimethyl-1-oxo-1,4a,5,5a,6,6a,7,8,9,10,10a,10b-dodecahydro-2H-6-oxapicen-3-yl furan; White Horehound Lactone
EINECS	Contact for details

Quality Control

Our Marrubiin is produced and tested under strict quality management systems to ensure high purity and batch-to-batch consistency. Quality is verified through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 165°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.