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1-(3-Fluorophenyl)-2-Thiourea CAS NO 458-05-9
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CAS No.:458-05-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-(3-Fluorophenyl)-2-Thiourea is a fluorinated aromatic thiourea derivative, a versatile organic building block of significant interest in advanced chemical synthesis. Its value lies in its unique molecular structure, which combines a fluorine-substituted phenyl ring with a reactive thiourea moiety, enabling precise modifications in complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, serving as a critical intermediate for developing active ingredients and functional materials.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
- Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
- Chemical Research & Development: Serves as a fundamental building block in organic chemistry for constructing heterocyclic compounds and complex molecules.
- Material Science: Investigated for use in the preparation of specialty polymers, ligands for catalysis, and advanced organic electronic materials.
- Analytical Chemistry: Can be employed as a derivatization agent or a standard in chromatographic analysis for fluorine-containing compounds.
Basic Information
| Product Name | 1-(3-Fluorophenyl)-2-Thiourea |
| CAS No. | 458-05-9 |
| Molecular Formula | C7H7FN2S |
| Molecular Weight | 170.21 g/mol |
| Synonyms | 3-Fluorophenylthiourea; 1-(3-Fluorophenyl)thiourea; (3-Fluorophenyl)thiourea; N-(3-Fluorophenyl)thiourea; Thiourea, N-(3-fluorophenyl)-; 3-Fluorophenyl-thioharnstoff; 1-(m-Fluorophenyl)-2-thiourea; m-Fluorophenylthiourea |
| EINECS | Contact for details |
Quality Control
Our 1-(3-Fluorophenyl)-2-Thiourea is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We are committed to meeting the stringent requirements of research and industrial applications, with specifications that can align with cGMP standards where required.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from direct light exposure.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Melting Point | 158 - 162 °C |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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