Description

4',5-Dihydroxy-7-Methoxyflavone is a naturally occurring flavonoid compound, also known as 5-Hydroxy-7-methoxyflavanone or 7-Methoxyapigenin, valued for its role as a key phytochemical building block and reference standard. This compound is essential for research and development in the nutraceutical and pharmaceutical sectors, where its biological activity is of significant interest. It is primarily sought by manufacturers and R&D laboratories focused on developing high-value botanical extracts, functional ingredients, and therapeutic agents.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in studies targeting inflammation, oxidative stress, and metabolic disorders.
• Nutraceutical & Dietary Supplement Formulation: Incorporated as a key bioactive marker in standardized botanical extracts, such as those derived from passionflower or other medicinal plants, to ensure potency and consistency.
• Cosmeceutical Ingredients: Serves as a functional ingredient in advanced skincare formulations for its potential antioxidant and skin-soothing properties.
• Analytical & Quality Control: Employed as a high-purity certified reference material (CRM) for HPLC, LC-MS, and other analytical methods to quantify flavonoids in complex matrices.
• Biochemical Research: Utilized in vitro and in vivo studies to investigate flavonoid metabolism, bioavailability, and structure-activity relationships (SAR).

Basic Information

Product Name	4',5-Dihydroxy-7-Methoxyflavone
CAS No.	437-64-9
Molecular Formula	C₁₆H₁₄O₅
Molecular Weight	286.28 g/mol
Synonyms	5-Hydroxy-7-methoxyflavanone; 7-Methoxyapigenin; 4',5-Dihydroxy-7-methoxyflavanone; 5-Hydroxy-7-methoxy-2-phenyl-4H-chromen-4-one; 7-Methoxy-4',5-dihydroxyflavone; 4',5-Dihydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one; Apigenin 7-methyl ether; Passionflower flavone marker.
EINECS	207-122-6

Quality Control

Our 4',5-Dihydroxy-7-Methoxyflavone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for identification, and residual solvent analysis, to ensure it meets the stringent requirements for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.