Description

Toluene-4-Sulfonic Acid 4-Fluoro-Butyl Ester is a specialized organosulfur compound that serves as a versatile building block and reagent in advanced organic synthesis. Its value lies in its dual functionality, combining a sulfonate ester leaving group with a fluorinated alkyl chain, enabling precise molecular modifications. This chemical is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and creating complex fluorinated intermediates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the introduction of fluorine atoms improves efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a fluorinated intermediate in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes.
• Polymer Modification Agent: Employed to introduce sulfonate ester and fluorine functional groups into polymer chains, altering surface properties and chemical resistance.
• Cross-coupling & Alkylation Reagent: Acts as an efficient alkylating agent in palladium-catalyzed cross-coupling reactions and other metal-mediated transformations.
• Organic Synthesis Research: A valuable tool in academic and industrial R&D labs for constructing complex molecular architectures and studying reaction mechanisms.

Basic Information

Product Name	Toluene-4-Sulfonic Acid 4-Fluoro-Butyl Ester
CAS No.	433-10-3
Molecular Formula	C11H15FO3S
Molecular Weight	246.30 g/mol
Synonyms	4-Fluorobutyl p-Toluenesulfonate; p-Toluenesulfonic Acid 4-Fluorobutyl Ester; 4-Fluorobutyl Tosylate; Tosyl Fluorobutyl Ester; 1-Fluoro-4-[(4-methylphenyl)sulfonyloxy]butane; 4-Methylbenzenesulfonic Acid 4-Fluorobutyl Ester; Butyl 4-fluoro tosylate; NSC 403798
EINECS	Contact for details

Quality Control

Our Toluene-4-Sulfonic Acid 4-Fluoro-Butyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. The container must be kept tightly closed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.25 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.