Description

1,1,1-Trifluoroacetone Oxime is a specialized fluorinated oxime compound that serves as a versatile building block in advanced organic synthesis. Its unique trifluoromethyl group imparts valuable properties such as enhanced lipophilicity and metabolic stability to target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of trifluoromethyl-substituted heterocycles and bioactive molecules, including potential enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the CF₃ group can improve activity and environmental profile.
• Material Science Research: Employed in the development of fluorinated polymers, liquid crystals, and specialty materials with tailored surface properties.
• Organic Synthesis Reagent: Acts as a precursor for various functional group transformations, including the generation of nitrile oxides for 1,3-dipolar cycloaddition reactions.
• Chemical Research & Development: A valuable tool for medicinal and process chemists exploring structure-activity relationships and novel synthetic pathways.

Basic Information

Product Name	1,1,1-Trifluoroacetone Oxime
CAS No.	431-40-3
Molecular Formula	C₃H₄F₃NO
Molecular Weight	127.06 g/mol
Synonyms	1,1,1-Trifluoroacetone Oxime; 3,3,3-Trifluoroacetone Oxime; 1,1,1-Trifluoro-2-propanone Oxime; 3,3,3-Trifluoro-2-propanone Oxime; Trifluoroacetoxime; TFAA Oxime; (Z)-1,1,1-Trifluoroacetone Oxime; (E)-1,1,1-Trifluoroacetone Oxime
EINECS	207-087-7

Quality Control

Our 1,1,1-Trifluoroacetone Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.