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2-Chloro-1-(Chloromethoxy)-1,1,2-Trifluoroethane CAS NO 428-92-2


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CAS No.:428-92-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Chloro-1-(Chloromethoxy)-1,1,2-Trifluoroethane is a specialized fluorinated organic compound valued for its unique reactivity and solvent properties. This chemical serves as a critical intermediate and reagent in advanced synthetic chemistry, enabling the introduction of fluorinated moieties into target molecules. It is primarily sought by R&D laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel compounds with enhanced properties.

Application

  • Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated structures for improved metabolic stability and bioavailability.
  • Agrochemical Synthesis: Serves as a key building block in the production of advanced herbicides, pesticides, and fungicides.
  • Fluorinated Polymer & Material Science: Acts as a monomer or modifying agent in the development of specialty polymers, coatings, and materials with specific chemical resistance or surface properties.
  • Organic Synthesis Reagent: Employed as a fluorinating agent or electrophile in complex organic reactions to construct challenging molecular architectures.
  • Refrigerant & Propellant Research: Investigated for potential applications in next-generation, low-global-warming-potential (GWP) refrigerant blends and aerosol systems.
  • Electronics Industry: Used in precision cleaning formulations and in the synthesis of chemicals for semiconductor manufacturing processes.

Basic Information

Item Details
Product Name 2-Chloro-1-(Chloromethoxy)-1,1,2-Trifluoroethane
CAS No. 428-92-2
Molecular Formula C3H2Cl2F3O
Molecular Weight 198.95 g/mol
Synonyms 1,1,2-Trifluoro-2-chloro-1-(chloromethoxy)ethane; Chloro(chloromethoxy)trifluoroethane; HCFC-253fb; 2-Chloro-1-(chloromethoxy)-1,1,2-trifluoroethane; 1-(Chloromethoxy)-2-chloro-1,1,2-trifluoroethane; Freon 253fb; R-253fb
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Quality Control

Our 2-Chloro-1-(Chloromethoxy)-1,1,2-Trifluoroethane is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms
Assay (GC) ≥ 98.0%
Water Content (KF) ≤ 0.1%
Density (at 20°C) ~1.55 g/mL
Boiling Point ~60-65°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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