Description

3-Butyn-2-One is a highly reactive acetylene derivative and a versatile alkyne-containing ketone building block. Its terminal alkyne and carbonyl functionalities make it a critical intermediate for synthesizing complex molecules through reactions like Sonogashira coupling, nucleophilic addition, and cycloadditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients, advanced materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing heterocyclic or acetylene moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and resins with tailored properties.
• Organic Synthesis & Research: A fundamental reagent for constructing complex molecular architectures in academic and industrial R&D laboratories.
• Ligand & Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Flavor & Fragrance Industry: Intermediate for the production of certain aroma chemicals and synthetic flavors.

Basic Information

Product Name	3-Butyn-2-One
CAS No.	423-60-5
Molecular Formula	C₄H₄O
Molecular Weight	68.07 g/mol
Synonyms	But-3-yn-2-one; 1-Butyn-3-one; 3-Butyn-2-one; Methyl ethynyl ketone; Acetylethylene; Ethynyl methyl ketone; 2-Butynone; Propiolyl methyl ketone
EINECS	207-033-9

Quality Control

Our 3-Butyn-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including Gas Chromatography (GC) and Infrared Spectroscopy (IR), to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat, sparks, and open flames. Due to its highly volatile nature, containers must be kept tightly sealed and stored upright in a secondary containment area. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.