Description

Trimethyloxonium Tetrafluoroborate is a powerful methylating agent and a highly reactive salt of the trimethyloxonium cation. Its primary value lies in its ability to efficiently transfer a methyl group to a wide variety of nucleophiles under relatively mild conditions, making it a crucial reagent in advanced organic synthesis and pharmaceutical research. This compound is essential for chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and fine chemicals where precise methylation is required.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the methylation of heterocycles, amines, alcohols, and carboxylic acids in the development of active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the synthesis of herbicides, fungicides, and pesticides where methyl group incorporation is a critical step.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, dyes, and flavor/fragrance compounds requiring selective methylation.
• Polymer Chemistry: Acts as an initiator or catalyst in certain polymerization reactions and for modifying polymer surfaces.
• Laboratory Research & Development: A staple reagent in academic and industrial R&D labs for method development and exploring new synthetic pathways.
• Material Science: Used in the surface functionalization of materials and in the synthesis of advanced organic electronic materials.

Basic Information

Item	Details
Product Name	Trimethyloxonium Tetrafluoroborate
CAS No.	420-37-1
Molecular Formula	C₃H₉BF₄O
Molecular Weight	147.91 g/mol
Synonyms	Trimethyloxonium Tetrafluoroborate; Trimethyloxonium Fluoborate; Trimethyloxonium BF4; Trimethyloxonium Boron Fluoride; Oxonium, trimethyl-, tetrafluoroborate(1-); Trimethyloxonium Tetrahydrofluoroborate; Me3OBF4; Trimethyloxonium Salt
EINECS	206-998-2

Quality Control

Our Trimethyloxonium Tetrafluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as purity, identity, and moisture content. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards, supporting its use in regulated research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle and store the product under an inert atmosphere (e.g., nitrogen or argon) and in a desiccator to maintain stability and purity. Long-term storage at 2-8°C is advised.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0 %
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.