Description

Fluorothioacetic Acid S-(2-Chloroethyl) Ester is a specialized organosulfur and organofluorine building block of significant interest in advanced chemical synthesis. This bifunctional compound, with CAS number 406-27-9, is valued for its unique reactivity profile, enabling the introduction of both fluorine and thioester moieties in a single molecular framework. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the construction of novel bioactive molecules and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in protease inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the preparation of novel herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Chemical Biology Probes: Serves as a versatile reagent for labeling and modifying proteins or other biomolecules due to the reactive chloroethyl thioester group.
• Material Science Research: Employed in the synthesis of fluorinated polymers or specialty materials with tailored surface properties.
• Cross-coupling Reactions: Acts as an electrophilic coupling partner in palladium-catalyzed or other metal-mediated reactions to form carbon-sulfur bonds.

Basic Information

Product Name	Fluorothioacetic Acid S-(2-Chloroethyl) Ester
CAS No.	406-27-9
Molecular Formula	C4H6ClFOS
Molecular Weight	156.60 g/mol
Synonyms	2-Chloroethyl Fluorothioacetate; S-(2-Chloroethyl) Fluorothioacetate; Fluorothioacetic Acid 2-Chloroethyl Ester; Acetic acid, fluorothio-, S-(2-chloroethyl) ester; 2-Chloroethanethiol Fluorocarbonate
EINECS	Contact for details

Quality Control

Our Fluorothioacetic Acid S-(2-Chloroethyl) Ester is produced under strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by GC or HPLC), identity confirmation (by IR and/or NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive and should be handled under an inert atmosphere for prolonged storage to maintain stability. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.