Description

5-Methyl-1H-Pyrazole-3-Carboxylic Acid is a versatile heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, offering a reactive scaffold for further functionalization. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those targeting inflammation, metabolic disorders, and central nervous system (CNS) diseases.
• Agrochemical Synthesis: Serves as a key building block for developing novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Used to create complexing agents and ligands for metal catalysts in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the development of advanced polymers, dyes, and other functional materials requiring specific heterocyclic motifs.
• Chemical Biology & Proteomics: Acts as a scaffold for designing enzyme inhibitors, molecular probes, and other tools for biological research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	5-Methyl-1H-Pyrazole-3-Carboxylic Acid
CAS No.	402-61-9
Molecular Formula	C5H6N2O2
Molecular Weight	126.11 g/mol
Synonyms	5-Methyl-1H-pyrazole-3-carboxylic acid; 5-Methylpyrazole-3-carboxylic acid; 3-Carboxy-5-methylpyrazole; 5-Methyl-3-pyrazolecarboxylic acid; 5-Methyl-1H-pyrazole-3-carboxylic acid; 5-Methyl-1H-pyrazol-3-carboxylic acid; 5-Methylpyrazole-3-carboxylic acid; 1H-Pyrazole-3-carboxylic acid, 5-methyl-
EINECS	206-940-5

Quality Control

Our 5-Methyl-1H-Pyrazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with ICH guidelines and can supply material suitable for use in cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.