Description

4-Fluorobenzenesulfonamide is a high-purity, versatile sulfonamide derivative serving as a critical building block in advanced organic synthesis. Its value lies in its role as a key intermediate for introducing the fluorobenzenesulfonyl moiety, which is essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients, including kinase inhibitors and herbicides.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom and sulfonamide group contribute to efficacy and environmental stability.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials requiring sulfonamide functionalities.
• Dye and Pigment Manufacturing: Can be utilized as an intermediate in the synthesis of specialized dyes and functional colorants.

Basic Information

Product Name	4-Fluorobenzenesulfonamide
CAS No.	402-46-0
Molecular Formula	C6H6FNO2S
Molecular Weight	175.18 g/mol
Synonyms	p-Fluorobenzenesulfonamide; Benzenesulfonamide, 4-fluoro-; 4-Fluorophenylsulfonamide; 4-Fluoro-benzenesulfonic acid amide; 1-Fluoro-4-sulfamoylbenzene; 402-46-0; p-Fluorophenylsulfonamide; 4-FBSA
EINECS	206-941-5

Quality Control

Our 4-Fluorobenzenesulfonamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.