Description

2-Iodo-4-Nitro-6-(Trifluoromethyl)Aniline is a high-value halogenated aniline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring iodine, nitro, and trifluoromethyl substituents, makes it an essential building block for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific receptors or enzymes.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and stability.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Synthesis: Acts as an intermediate for producing complex azo dyes and pigments with specific colorfastness and light-absorption properties.
• Cross-Coupling Reactions: The iodine substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Iodo-4-Nitro-6-(Trifluoromethyl)Aniline
CAS No.	400-69-1
Molecular Formula	C7H4F3IN2O2
Molecular Weight	332.02 g/mol
Synonyms	2-Iodo-4-nitro-6-(trifluoromethyl)benzenamine; 4-Nitro-2-iodo-6-(trifluoromethyl)aniline; 6-Trifluoromethyl-2-iodo-4-nitroaniline; Benzenamine, 2-iodo-4-nitro-6-(trifluoromethyl)-; 2-Iodo-4-nitro-alpha,alpha,α-trifluoro-m-toluidine; 2-Iodo-4-nitro-6-trifluoromethylaniline; 2-Iodo-4-nitro-6-trifluoromethylphenylamine
EINECS	Contact for details

Quality Control

Our 2-Iodo-4-Nitro-6-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent composition. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong acids, bases, and reducing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.